Table 3.

Bacterial species whose abundance is statistically different between cases with obesity and eutrophic controls.

Bacteria	Subjects with Obesity (Cases, n = 78)	Eutrophic Individuals (Controls, n = 25)	p-Value *	q-Value **	Model 1 (q-Value)	Model 2 (q-Value)
Abiotrophia defectiva	0.0001 (0.0001–0.2825)	0.0001 (0.0001–0.001)	0.0001	0.001
Actinomyces odontolyticus	0.0001 (0.0001–1.643)	0.0001 (0.0001–0.652)	0.010	0.020	0.037	0.047
Allisonella histaminiformans	0.0001 (0.0001–5.260)	0.0001 (0.0001–0.001)	0.0001	0.001	0.026	0.042
Bacteroides eggerthii	3.573 (1.903–10.086)	9.769 (3.32–11.892)	0.039	0.042	0.049	0.049
Barnesiella intestinihominis	2.885 (0.730–5.809)	1.889 (0.001–3.361)	0.019	0.036	0.047	0.047
Dorea longicatena	9.959 (9.295–10.557)	9.547 (8.887–10.268)	0.039	0.045	0.049	0.049
Haemophilus parainfluenzae	5.834 (2.990–7.775)	8.254 (6.181–10.708)	0.001	0.002	0.003	0.032
Howardella ureilytica	2.439 (0.0001–6.303)	0.0001 (0.0001–2.476)	0.010	0.023	0.038	0.037
Lactobacillus curvatus	0.0001 (0.0001–1.626)	0.0001 (0.0001–0.001)	0.0001	0.001	0.046	0.050
Megamonas funiformis	0.0001 (0.0001–0.974)	0.0001 (0.0001–0.001)	0.0001	0.001	0.050	0.143
Mitsuokella jaladudinii	0.0001 (0.0001–2.521)	0.0001 (0.0001–0.001)	0.002	0.030
Odoribacter laneus	0.0001 (0.0001–2.707)	0.0001 (0.0001–1.015)	0.027	0.040	0.291	0.605

Data are shown as median (25th–75th percentiles). * p-values were obtained using Student t-test with the log-transformed variable. ** Raw p-values were corrected by false discovery rate (FDR; q-value). Regression analysis were done to compute (i) model 1 (adjustment for age and gender) and (ii) model 2 (adjustment for age, gender, triglycerides and HOMA-IR). Statistical significance is shown as q-value < 0.05.