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. 2020 Dec 15;12(12):3770. doi: 10.3390/cancers12123770

Table 1.

Origin of cancer-associated fibroblasts (CAFs) and their markers.

Cell Type Selected Markers/Factors Mentioned in the References Reference
Pancreatic stellate cells Desmin, GFAP, acetylcholine receptors [20]
Mesenchymal stem cell-derived cancer-associated fibroblasts (Gastric cancer) IL-6, Wnt5a, BMP4 [32]
Bone-marrow derived mesenchymal stem cells (Breast cancer) CCL5/RANTES [33]
Cancer-associated mesenchymal stem cells (Pancreatic cancer) GM-CSF, CD44+/CD73+/CD90+/CD49α+ [34]
Adipose-derived mesenchymal stem cells (obese donors) (ovarian cancer) ACTA2, VEGF, FAP, S100A4 (FSP), CSPG4 (NG2) [35]