Table 2.
Coenzyme Q10 status, oxidative stress, and antioxidant capacity of the subjects.
| Elderly 2 | Middle-Age 2 | |||||
|---|---|---|---|---|---|---|
| OA (N = 74) | Non-OA (N = 33) | p Value 3 | OA (N = 26) | Non-OA (N = 67) | p Value 3 | |
| Coenzyme Q10 (µM) 1 | 0.41 ± 0.15 (0.41) | 0.47 ± 0.22 (0.46) | 0.18 | 0.44 ± 0.13 (0.42) | 0.47 ± 0.18 (0.43) | 0.44 |
| Coenzyme Q10/TC (µmol/mmol) | 0.08 ± 0.03 (0.08) | 0.10 ± 0.04 (0.09) | 0.06 | 0.09 ± 0.03 (0.09) | 0.09 ± 0.03 (0.09) | 0.99 |
| Oxidative stress | ||||||
| MDA (µM) | 2.6 ± 0.5 (2.5) | 2.7 ± 0.6 (2.6) | 0.29 | 2.5 ± 0.4 (2.5) | 2.7 ± 0.5 (2.7) | 0.09 |
| Protein carbonyl (nmole/mg protein) | 0.38 ± 0.06 (0.37) | 0.38 ± 0.07 (0.38) * | 0.96 | 0.36 ± 0.05 (0.37) | 0.34 ± 0.07 (0.33) | 0.02 |
| Antioxidant capacity | ||||||
| Serum TAC (mM Trolox) | 5.8 ± 0.5 (5.7) | 5.4 ± 0.3 (5.4) | <0.01 | 5.9 ± 0.4 (6.0) | 5.4 ± 0.3 (5.5) | <0.01 |
| RBC TAC (mM Trolox) | 10.2 ± 0.7 (10.1) * | 10.0 ± 0.5 (10.0) | 0.16 | 10.6 ± 0.7 (10.4) | 10.1 ± 0.5 (10.0) | <0.01 |
1 Means ± SD (medians). 2 Elderly: ≥65 y; middle-age: 40–64 y. 3 Comparison between OA and non-OA in the same age group. * Comparison between different age groups with OA or without OA, p < 0.05. MDA, malondialdehyde; OA, osteoarthritis; RBC, red blood cell; TAC, total antioxidant capacity; TC, total cholesterol.