Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Receptors at the brain endothelium initiating receptor-mediated transcytosis.
| Receptor | Natural Ligands | Direction |
| Transferrin (TfR) | Transferrin | Blood–Brain |
| Insulin (IR) | Insulin | Blood–Brain |
| Leptin (LepR) | Leptin | Blood–Brain |
| Low-density lipoprotein receptor related protein 1 (LRP1) | Lipoproteins, apolipoprotein E (ApoE), α2-macroglobulin, aprotinin, amyloid-ß | Blood–Brain Brain–Blood |
| Receptor for advanced glycosylation end products (RAGE) | Glycosylated end products, amyloid-ß | Blood–Brain |
