Table 2.
Correlations of GJB2 genotypes and severity of hearing loss.
| Genotypes | No of Subjects | Mild (21–40 dB) | Moderate (41–70 dB) | Severe (71–90 dB) | Profound (>90 dB) | |
|---|---|---|---|---|---|---|
| c.35delG Homozygous | c.35delG/c.35delG | 57 | 2 | 7 | 20 | 28 |
| c.35delG Heterozygous | c.35delG/wt | 26 | 4 | 11 | 7 | 4 |
| c.35delG Compound Heterozygous | c.35delG/c.101T>C | 10 | - | 6 | 2 | 2 |
| c.35delG/c.313_326del14 | 6 | - | 1 | 2 | 3 | |
| c.35delG/c.-23+1G>A | 4 | - | - | 1 | 3 | |
| c.35delG/c.71G>A | 8 | - | 1 | 3 | 4 | |
| c.35delG/c.551G>C | 2 | - | - | - | 2 | |
| Non-35delG Compound Heterozygous | c.79G>A/c.380G>A | 1 | - | 1 | - | - |
| c.79G>A/c.341C>G/C.380G>A | 4 | 1 | 3 | - | - | |
| c.79G>A/c.39G>A | 4 | 2 | 2 | - | - | |
| Non-35delG Heterozygous | c.101T>C/wt | 9 | 5 | 2 | 1 | 1 |
| c.71G>A/wt | 7 | - | 5 | 1 | 1 | |
| c.457G>A/wt | 5 | 1 | 2 | 2 | - | |
| c.313_326del14/wt | 2 | - | 1 | 1 | - | |
| c.269T>C | 3 | - | - | 2 | 1 | |
| c.109G>A/wt | 3 | - | - | 2 | 1 | |
| c.551G>C/wt | 2 | - | 1 | 1 | - | |
| c.380G>A/wt | 2 | 2 | - | - | - | |
| c.100A>T | 3 | 2 | 1 | - | - | |
| Total | 158 | 19 | 44 | 45 | 50 | |