Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Dec 15;25(24):5933. doi: 10.3390/molecules25245933

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Structural representations (a) of Ubc7p (yellow, PDB 2UCZ) overlaid with Ubc7p:U7BR (green, PDB 4JQU) highlighting the minimal differences within the two structures with a dashed box. A zoomed-in representation (b) showing loop $α$ $_{2}$ $α$ $_{3}$ shifts away from the Cys89 once U7BR binds to Ubc7p. This interaction also introduces changes in loop $β$ $_{4}$ $α$ $_{2}$ , highlighted by the structural differences in side-chains Leu105 and Glu108. Figure adapted from Metzger et al. [84].