CAR |
Chimeric antigen receptor |
ITIM |
immune tyrosine-based inhibitory motif |
MAC |
membrane attacking complex |
FcγR |
Fc-gamma receptor |
ITAM |
immune tyrosine-based activation motif |
mAbs |
monoclonal antibodies |
NHL |
non-Hodgkin lymphoma |
CLL |
chronic lymphocytic leukemia |
CTCL |
cutaneous T cell lymphoma |
PTCL |
peripheral T cell lymphoma |
NK |
natural killer |
DCs |
dendritic cells |
TM4SF |
transmembrane-four superfamily proteins |
TEM |
tetraspanin-enriched membrane microdomain |
CXCL |
chemokine (C-X-C motif) ligand |
APC |
antigen-presenting cell |
MHC |
major histocompatibility complex |
TCR |
T cell receptor |
BCR |
B cell receptor |
VCAM-1 |
vascular cell adhesion molecule-1 |
EV |
extracellular vesicles |
SOCS3 |
suppressor of cytokine signaling 3 |
Bcl-2 |
B cell lymphoma 2 |
R-CHOP |
rituximab+chemotherapy |
DLBCL |
diffuse large B cell lymphoma |
IPI |
International Prognostic Index |
PKC |
protein kinase C |
Jak |
Janus Kinase |
STAT3 |
Signal Transducer and Activator of Transcription 3 |
PI3K |
phosphatidylinositol 3-kinase |
NF-κB |
nuclear factor kappa-light-chain-enhancer of activated B cells |
FoxO3a |
Forkhead box O3 |
GSK3 |
glycogen synthase kinase 3 |
AML |
acute myeloid leukemia |
NSCLC |
non-small cell lung cancer |
IL |
interleukin |
IgG |
Immunoglobulin G |
SHP-1 |
Src homology region 2 domain-containing phosphatase-1 |
IL-7R |
interleukin-7 receptor |
CDC |
complement-dependent cytotoxicity |
ADCC |
antibody-dependent cellular cytotoxicity |
ADCP |
antibody-dependent cellular phagocytosis |
PDX |
patient derived xenografts |
scFv |
single-chain variable fragment |
MCL |
mantle cell lymphoma |