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. 2020 Dec 15;10(12):423. doi: 10.3390/membranes10120423

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Score of inflammatory reaction according to ISO 10993-6:2016 of Bio-Gide^® and Lyostypt^® groups after 7, 21, and 63 days of implantation. The values obtained from Bio-Gide^® and Lyostypt^® groups were subtracted from the control (Sham group). The results are presented in the box as median, minimum, and maximum. The groups were ranked according to the criteria in ISO 10993-6:2016: non-irritant (0.0 to 2.9), slight irritant (3.0 to 8.9), moderate irritant (9.0 to 15.0), and severe irritant (>15).