Table 1.

The main studies conducted with extracts derived from miracle berry.

Start Material	Solvent Extract	Effects	Type of Study	Ref.
Powder seeds	95% Ethanol	Cholesterol-lowering agent	Preclinical	[49]
Air-dried leaves	80% Methanol	Antidiabetic	Preclinical	[45,48]
Air-dried skin+pulp	95% EtOH	Uptake of glucose	In vitro (C2C12)	[43]
Miracle fruit powder	Water/butanol	Antioxidant; Anti-hyperuricemia	In vitro, Preclinical	[50]
Leaves, stems, and berries dried	80% MeOH, 10% EtOH	Reduce proliferation of colorectal cancer cell lines	In vitro	[51]
Stems	MeOH	Reduce proliferation in melanoma cell lines	In vitro	[36]
Pulp and fruit	MeOH-fruit	Anti-tyrosinase and antioxidation effects	In vitro	[44]
	CHCl3-pulp
Miracle fruit powder	No extraction	Improve insulin resistance	Preclinical	[41]