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. 2020 Dec 15;21(24):9552. doi: 10.3390/ijms21249552

Table 2.

Amyloidogenic regions predicted by different programs for SARS-CoV-2 spike protein.

Software Amyloidogenic Regions for SARS-CoV-2 Spike Protein (https://www.uniprot.org/uniprot/P0DTC2)
AGGRESCAN
(UAB, Barcelona, Spain http://bioinf.uab.es/aggrescan/)
1–8, 10–16, 31–38, 40–47, 50–56, 58–70, 86–91, 100–109, 114–133, 140–145, 162–167, 189–208, 231–247, 260–271, 303–311, 331–336, 338–354, 362–383, 390–400, 428–437, 448–457, 484–490, 508–520, 584–588, 590–599, 610–617, 666–671, 688–698, 716–727, 729–745, 751–759, 761–768, 783–787, 797–805, 817–833, 853–861, 864–870, 872–914, 961–982, 1000–1013, 1044–1052, 1058–1068, 1097–1101, 1124–1137, 1171–1179, 1207–1249.
PASTA 2.0
(University of Padova, Padova, Italy http://protein.bio.unipd.it/pasta2/)
1214–1244.
Waltz
(Switch Laboratory, Leuven, Belgium http://waltz.switchlab.org/index.cgi)
1–9, 88–95, 115–137, 141–146, 199–204, 261–271, 275–280, 365–378, 447–455, 485–496, 537–544, 608–618, 689–697, 703–727, 798–806, 913–940, 969–974, 1003–1015, 1063–1068, 1117–1122, 1175–1179, 1206–1233.
FoldAmyloid
(Institute of Protein Research of the Russian Academy of Sciences, Pushchino, Russia
http://bioinfo.protres.ru/fold-amyloid/)
1–10, 34–38, 53–69,100–108,116–120, 126–135, 141–146, 174–178, 190–195, 235–244, 264–269, 274–278, 327–331, 348–353, 366–370, 389–395, 431– 436, 450–457, 487–492, 507–519, 539–543, 560–564, 582–586, 609–613, 691–697, 718–722, 738–743, 751– 755, 780–784, 799–804, 819–825, 875–880, 894–907, 993–999, 1005–1014, 1047–1051, 1060–1067, 1101–1105, 1127–1132, 1210–1239.