Table 1.

Table of SF3B1 missense mutation frequency of uveal melanoma (UM) patients. Reference sequence: NM_012433.3(SF3B1); Build: hg38 (data from: Catalogue of Somatic Mutations in cancer v92, 27-08-2020, [46]).

Position	Exon	AA Mutation	CDS Mutation	Effect	Frequency (n = 122, %)
2: 197402759	14	p.R625H	c.1874G > A	Missense	61 (50%)
2: 197402760	14	p.R625C	c.1873C > T	Missense	38 (31%)
2: 197402759	14	p.R625L	c.1874G > T	Missense	7 (5.7%)
2: 197402760	14	p.R625G	c.1873C > G	Missense	1 (0.8%)
2: 197402759	14	p.R625P	c.1874G > C	Missense	1 (0.8%)
2: 197402760	14	p.R625S	c.1873C > A	Missense	1 (0.8%)
2: 197402775	14	p.M620V	c.1858A > G	Missense	1 (0.8%)
2: 197402767	14	p.E622D	c.1866G > C	Missense	1 (0.8%)
2: 197402766	14	p.Y623H	c.1867T > C	Missense	1 (0.8%)
2: 197402636	14	p.K666T	c.1997A > C	Missense	2 (1.6%)
2: 197402110	15	p.K700E	c.2098A > G	Missense	1 (0.8%)
2: 197401765	16	p.E783K	c.2347G > A	Missense	1 (0.8%)
2: 197401771	16	p.D781N	c.2341G > A	Missense	1 (0.8%)
2: 197401887	16	p.G742D	c.2225G > A	Missense	1 (0.8%)
2:197396227	23	p.C1123Y	c.3368G > A	Missense	1 (0.8%)