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Schematic description of sample collection and processing from human pre-ovulatory follicles of polycystic ovary syndrome (PCOS) patients and fertile control group. COC—cumulus oocyte complex (green), FF—cell-free follicular fluid (yellow) containing extracellular vesicles (EV, black) and non-EV-bound RNA (blue), IVF—in vitro fertilization, MGC—mural granulosa cells (red).
