Table 1.

Inclusion and exclusion criteria used.

Parameter	Inclusion	Exclusion
Compound’s target	A plasmodial kinase clearly defined as target	Target is not a plasmodial kinase or target is undefined
Study type	Medicinal chemistry studies Biology studies listing properties of one or more chemical compounds	In silico studies without biological tests Natural extract studies without active compounds determined Biological studies on protein pathways/phenotypic changes using only genes disruption or polypeptides