Table 11.
Taketinib and its analog as inhibitors of PfPK9.
| Compound | R | Kd(app) PfPK9 (µM) | HuH7 P. berghei Infected Cell Load EC50 (µM) |
|---|---|---|---|
| 85 (taketinib) | NH2 | 0.46 | 7.3 |
| 86 | OH | 4.1 | 43 |
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