Skip to main content
. 2020 Dec 16;21(24):9575. doi: 10.3390/ijms21249575

Figure 3.

Figure 3

Regulation of the mammalian target of rapamycin (mTOR) complex 2 signaling pathway by resveratrol. NK92 cells were deprived of interleukin (IL)-2 for 24 h and then treated with IL-2 (5 ng/mL) with or without 20 μM resveratrol for 30 min. (a) Western blot showing phosphoinositide-dependent kinase-1 (PDK1) (pSer241) and rictor (pThr1135) expression and total form. Data are shown as the mean ± SEM of four independent experiments. (b) Western blot showing phosphatase and tensin homolog (PTEN) and ribosomal protein S6 kinase beta-1 (S6K1) (pThr389) expression and total form. Data are shown as the mean ± SEM of three independent experiments. Asterisks indicate statistical significance using the Student’s t-test: * p < 0.05, ** p < 0.01, *** p < 0.001, ns: not significant (p > 0.05).