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. 2020 Dec 16;12(12):3795. doi: 10.3390/cancers12123795

Table 4.

Toxicity of the most used chemotherapeutics and their influence on the fetus [65,66].

Drug Fetal Abnormalities Comments
Cisplatin Impaired development, hypoacusia, neutropenia, ventriculomegaly, hair loss -
Carboplatin None -
Paclitaxel Myelosuppression, pyrolic stenosis Single cases
Etoposide Pancytopenia, hypoacusia, secondary leukemias Particular fear of secondary tumors
Bleomycin Syndactyly -
Vinblastine Syndactyly, plagiocephaly Safer than etoposide