Figure 4.

Representation of a future experiment, where gelsolin is inhibited by polyphosphoinositides (PPI) in Arabidopsis thaliana under cadmium stress. The vesicles move (black arrow) between the endoplasmic reticulum (ER), Golgi network, vacuole, and the PM. Cadmium stress triggers a callose response, which is sorted and packaged in vesicles for unloading at the PM. The vesicles attaches to the molecular motors (^), which facilitates the movement on the actin filaments. The induced PPI inhibits gelsolin, which subsequently cannot cut the actin filaments, and therefore the vesicles can reach the PM unhindered.