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. 2020 Dec 16;21(24):9582. doi: 10.3390/ijms21249582

Table 1.

miRNA-ceRNAs networks experimentally validated associated with NDDs.

Disease ncRNA miRNA mRNA Sample Ref.
AD lncRNA BACE1-AS miR-29, miR-485, miR-761,
miR-124 and miR-107
BACE1 Computational analysis from human data and cellular and mouse models [24]
miR-214-3p - [25]
miR-132-3p - [26]
XIST miR-124 BACE1 Cellular and mouse models [27]
miR-132 - [28]
NEAT1 miR-124 BACE1 Cellular and mouse models [29]
miR-107 - [30]
SOX21-AS1 miR-107 - Cellular model [31]
NEAT1
HOTAIR MALAT1
miR-107,
miR-103,
miR-16, miR-195, miR-15a and miR-15b
CDK5R1 Cellular model
[32]
MALAT1 miR-125b CDK5, FOXQ1
and PTGS2
Cellular and rat models [33]
miR-30b CNR1 [34]
TUG1 miR-15a ROCK1 Cellular and mouse models [35]
SNHG1 miR-137 KREMEN1 Cellular model and human primary cell culture [36]
miR-361-3p ZNF217 [37]
lncRNA-ATB miR-200 ZNF217 Cellular model [38]
LINC00094 miR-224-4p
miR-497-5p
SH3GL2 Cellular model [39]
MIAT miR-150-5p VEGF Cellular and mouse models [40]
Rpph1 miR-326 PKM2 Cellular and mouse models [41]
miR-122 Wnt1 [42]
miR-330-5p CDC42 [43]
linc00507 miR-181c-5p MAPT
TTBK1
Cellular and mouse models [44]
lnc-ANRIL mir-125a TNF-α, IL1B IL6 and IL17 Cellular model [45]
circRNA ciRS-7 miR-7 UBE2A Human brain [46]
* miR-7 * NF-Κb/p65 Cellular models [47,48,49]
circ_0000950 miR-103 PTGS2 Cellular models [50]
circHDAC9 miR-138 Sirt1 Cellular and mouse models [51]
miR-142-5p - [52]
PD pseudogene GBAP1 miR-22-3p GBA Cellular models [53]
lncRNA SNHG1 miR-153-3p
miR-15b-5p
miR-7
miR-221/222
PTEN
SIAH1, GSK3β
NLRP3
CDKN1B (p27)
Cellular and mouse models [54]
[55,56]
[57]
[58]
HAGLROs miR-100 ATG10 Cellular and mouse models [59]
HOTAIR miR-874-5p ATG10 Cellular and mouse models [60]
miR-126-5p RAB3IP [61]
NEAT1 miR-212-5p RAB3IP Cellular models [62]
miR-1277-5p ARHGAP26 [63]
miR-124 - [64]
AL049437 miR-205-5p MAPK1 Cellular and mouse models [65]
MALAT1 miR-205-5p LRRK2 Cellular and mouse models [66]
miR-124 DAPK1 [67,68]
miR-129 SNCA (α-syn) [69]
SNHG14 miR-133b SNCA Cellular and mouse models [70]
LincRNA-p21 miR-1277-5p SNCA Cellular and mouse models [71]
miR-181 family PRKCD
(PKC-δ)
[72]
miR-625 TRPM2 [73]
GAS5 miR-223-3p NLRP3 Cellular and mouse models [74]
BDNF-AS miR-125b-5p - Cellular and mouse models [75]
Mirt2 miR-101 - Cellular model [76]
lncRNA H19 miR-301b-3p HPRT1 Computational analysis from human data and cellular and mouse models [77]
miR-585-3p PIK3R3 [78]
circRNA * ciRS-7 miR-7 SNCA Cellular and mouse models [79,80,81,82,83]
circSNCA miR-7 SNCA Cellular model [84]
circzip-2 * miR-60 M60.4ZK470.2, igeg-2 and idhg-1 Worm model [85]
circDLGAP4 miR-134-5p CREB Cellular and mouse models [86]
MS lncRNA Gm15575 miR-686 CCL7 Cellular and mouse models [87]
PVT1 miR-21-5p SOCS5 Cellular and mouse models [88]
TUG miR-9-5p NFKB1 (p50) Cellular and mouse models [89]
HOTAIR miR-136-5p AKT2 Cellular and mouse models [90]
GAS5 miR-137 - Human blood [91]
circRNA hsa_circ_0106803 * miR-149 * ASIC1a Human blood (PMBCs) [92,93]
hsa_circ_0005402
hsa_circ_0035560
* 14 miRNAs
(miR-1248, miR-766)
- Human blood (PMBCs) [94]
SCA7 lncRNA lnc-SCA7 miR-124 ATXN7 Human samples, and cellular and animal models [95]

* Experimental validation is needed.