Table 6.
Odds ratio for developing preeclampsia based on the combination of MAP and the CD44/FKBPL ratio (cut-off 143.6 or 155.1) at 20 weeks of gestation
| MAP and CD44/FKBPL | Controls, n (%) | Cases, n (%) | OR (95% CI) | P-value | ||||
|---|---|---|---|---|---|---|---|---|
| 143.6 | 155.1 | 143.6 | 155.1 | 143.6 | 155.1 | 143.6 | 155.1 | |
| Low riska | 16 (29) | 18 (33) | 7 (13) | 8 (15) | 1.0 | 1.0 | ||
| Medium risk 1b | 13 (24) | 11 (20) | 14 (26) | 13 (24) | 2.46 (0.78-7.90) | 2.66 (0.84-8.46) | 0.130 | 0.098 |
| Medium risk 2c | 12 (22) | 15 (27) | 9 (17) | 13 (24) | 1.71 (0.49-5.92) | 1.95 (0.64-5.95) | 0.394 | 0.241 |
| High riskd | 14 (25) | 11 (20) | 24 (44) | 20 (37) | 3.92 (1.30-11.84) | 4.09 (1.35-12.43) | 0.016 | 0.013 |
Cut off value for CD44/FKBPL ratio (143.6 or 155.1) and MAP (82.5 mmHg) were determined based on the ROC analysis. Bolded P-values indicate a significant difference between the two groups.
Abbreviations: CI, confidence interval; OR, odds ratio.
aLow risk: Low CD44/FKBPL and low MAP (reference category).
bMedium risk 1: High CD44/FKBPL and low MAP.
cMedium risk 2: Low CD44/FKBPL and high MAP.
dHigh risk: High CD44/FKBPL and high MAP.