Figure 2.

Serum bone turnover markers before and after treatment by group (median, interquartile range). This figure shows serum concentrations of procollagen type I amino-terminal propeptide (P1NP; A, C, E, and G) and C-terminal telopeptide of type I collagen (CTX; B, D, F, and H) in various groups: A and B, placebo; C and D, dimethandrolone undecanoate (DMAU) 100 mg; E and F, DMAU 200 mg; and G and H, DMAU 400 mg on day 1 (in blue; before treatment start) and day 28 (in red; end of treatment). *P less than .05 on Wilcoxon signed-rank test for within-group change.