Figure 3.

Fluorescent protein nanocapsules. (a) Schematic representation of green fluorescence protein (GFP) coated MSPs. (b) TEM images of GFP-coated MSPs before (left) and after silica dissolution (right). Resulting HC@GFP capsules after protein crosslinking and MSP core dissolution. (c) Confocal microscopy single plane image of the fluorescent HC@GFP nanocapsules. (right) Fluorescent protein profile obtained of one of the capsules (arrow) where a central cavity devoid of protein (empty core) can be identified. Scale bar corresponds to 100 nm.