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. 2020 Dec 16;21(24):9573. doi: 10.3390/ijms21249573

Figure 4.

Figure 4

(a) Scheme of fluorescent PEE-DiI filled capsule design. MSPs are loaded with DiI and coated with a fluorescent PEE, in this case, fluorescein isothiocyanate (FITC) poly-L lysine (PLL-FITC). (b) Single plane confocal images of Hela cells treated with DiI filled PEE capsules (DiI-HC@PLL-FITC) for 96 h. (inset #1) Magnification of the area allows the identification of individual intracellular capsules and their contents. (inset #2) Filled particles loaded with DiI (orange). (inset #3) FITC empty fluorescent capsules (green). (inset #4) Capsules releasing DiI (white arrow) intermingle with empty capsules (green arrows) and filled intact capsules (red arrow) within the cellular cytoplasm. Cell nuclei are stained with Hoechst (blue channel).

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