Table 1.
Evaluation effects of different doses of MgSO4 on lipid peroxidation, protein carbonyl formation, and glutathione content against induced hypoxia by different methods.
Parameter ⟶ | Group | LPO (μg/mg protein) | PC (μg/mg protein) | GSH (μg/mg protein) |
---|---|---|---|---|
Hypoxia type ↓ | ||||
Asphyctic | Con (NS) | 0.8770 ± 0.036 | 1.320 ± 0.097 | 0.270 ± 0.021 |
Phenytoin | 0.7560 ± 0.033 | 0.8527 ± 0.035∗ | 0.1187 ± 0.010∗ | |
Mg 400 | 0.3000 ± 0.096 | 0.7573 ± 0.035∗ | 0.1813 ± 0.045 | |
Mg 500 | 0.6270 ± 0.027 | 0.7883 ± 0.028∗ | 0.2123 ± 0.042∗ | |
Mg 600 | 0.5020 ± 0.210∗ | 0.6873 ± 0.188∗∗ | 0.1233 ± 0.007 | |
| ||||
Circulatory (NaF) | Con (NS+NaF) | 0.3468 ± 0.038 | 1.532 ± 0.426 | 0.1174 ± 0.011 |
NaF+Mg 400 | 0.2307 ± 0.026 | 0.4417 ± 0.032∗ | 0.1077 ± 0.005 | |
NaF+Mg 500 | 0.2470 ± 0.062 | 0.5247 ± 0.074∗ | 0.1143 ± 0.014 | |
NaF+Mg 600 | 0.1470 ± 0.010∗ | 0.7007 ± 0.060 | 0.1163 ± 0.004 | |
| ||||
Haemic (NaNO2) | Con (NS+NaNO2) | 0.6373 ± 0.039 | 1.532 ± 0.426 | 0.148 ± 0.022 |
NaNO2+Mg 400 | 0.4913 ± 0.044 | 0.4343 ± 0.118∗ | 0.0950 ± 0.006 | |
NaNO2+Mg 500 | 0.2920 ± 0.051∗ | 0.8483 ± 0.192 | 0.0846 ± 0.004∗ | |
NaNO2+Mg 600 | 0.2860 ± 0.112∗ | 1.081 ± 0.152 | 0.0993 ± 0.005 |
Data are presented as mean ± SD of 6 animals in each group. ∗P < 0.05 and ∗∗P < 0.01: significantly compared with each control group.