Figure 2.

θ-to-γ phase-amplitude coupling (PAC) analysis process. (a) Filtered LFP in θ (black trace) and γ bands (coloured traces) are represented; θ trace is the average of n theta cycles, aligned around their maximum amplitude (downscaled to fit γ amplitude); each θ cycle-concurrent γ activity is presented in superposition using the abovementioned alignment. (b) Average normalized γ band scalogram (colour scale) relative to the θ phase (illustrated as a white trace). (c) Normalized γ band spectral power average as a function of the θ phase. (d) Average vector of (c) indicating dominant-phase θ-to-γ PAC.