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. Author manuscript; available in PMC: 2022 Feb 1.
Published in final edited form as: J Neurochem. 2020 Jul 11;156(4):435–444. doi: 10.1111/jnc.15110

Fig. 1. Lysine in the lariat loop interacts with phosphates.

Fig. 1.

(a) Lys301 in mouse arrestin-1 engages one of the rhodopsin-attached phosphates (phospho-threonine 336) (PDB ID: 5W0P)(Zhou et al. 2017); (b) Lys294 in bovine arrestin-2 binds one of the phosphates in multi-phosphorylated C-terminal peptide of V2 vasopressin receptor (phospho-threonine 360) (PDB ID: 4JQI) (Shukla et al. 2013); (c) Lys295 in bovine arrestin-3 binds one of the IP6 phosphates (PDB ID: 5TV1) (Chen et al. 2017). In all panels arrestins are shown as flat ribbons, β-strands are colored light blue, α-helices red, β-turns green. Images were created in DS ViewerPro 6.0 (Accelrys Software, Inc; San Diego, CA).