Table 3.

Univariate and Multivariable Models for Death Prior to Hospital Discharge and for Vineland Adaptive Behavior Scales, Second Edition, Composite Score <85 or Death within 12 Months

	Death prior to hospital discharge (n=99)		VABS-II <85 or death within 12 months after ECMO among survivors to hospital discharge with follow-up data (n=43)
Variable/Outcome	Unadjusted OR (95% CI)	Adjusted OR (95% CI)	Unadjusted OR (95% CI)	Adjusted OR (95% CI)
Age category
Neonate (<30 d)	1.10 (0.39, 3.05)	3.25 (0.87, 12.20)	0.26 (0.05, 1.42)	0.18 (0.02, 1.84)
Infant (30 d to <1 y)	Ref	Ref	Ref	Ref
Child (1 to <12 y)	0.78 (0.22, 2.77)	1.61 (0.38, 6.77)	0.80 (0.10, 6.35)	0.57 (0.05, 6.23)
Adolescent (≥12 y)	0.80 (0.15, 4.26)	1.28 (0.21, 7.85)	0.15 (0.01, 2.06)	0.13 (0.01, 2.14)
Gender
Female	Ref	Ref	Ref	Ref
Male	1.20 (0.54, 2.68)	0.89 (0.36, 2.22)	1.22 (0.36, 4.21)	3.04 (0.53, 17.33)
Primary ECMO indication
Respiratory failure	Ref	Ref	Ref	Ref
Cardiac failure	3.29 (1.19, 9.07)	4.66 (1.53, 14.20)	1.90 (0.47, 7.70)	2.01 (0.37, 11.07)
ECPR	5.36 (1.57, 18.25)	10.65 (2.41, 47.04)	3.25 (0.43, 24.84)	1.82 (0.14, 23.65)
Sepsis	1.04 (0.17, 6.22)	1.41 (0.22, 8.99)	0.72 (0.06, 8.46)	0.80 (0.05, 11.89)
Pre-ECMO cardiac arrest
No	Ref	Ref	Ref	Ref
Yes	2.38 (1.05, 5.43)	1.75 (0.56, 5.42)	0.69 (0.17, 2.80)	0.14 (0.01, 1.93)
Neuroimaging abnormality
Absent	Ref	Ref	Ref	Ref
Present	1.25 (0.56, 2.79)	1.14 (0.46, 2.84)	4.13 (1.13, 15.10)	5.43 (1.13, 26.12)

CI, confidence interval; ECMO, extracorporeal membrane oxygenation; ECPR, extracorporeal cardiopulmonary resuscitation; OR, odds ratio; VABS-II, Vineland Adaptive Behavior Scales, Second Edition.