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. 2020 Dec 17;10(12):999. doi: 10.3390/brainsci10120999

Table 2.

Multifactorial interaction comparisons (repeated measure ANOVA) and simple means comparisons (t-tests) of RWM errors. Sidak corrections used for t-tests with multiple comparisons. (* for a value indicates a significant paired difference, see significance column, * in a column title indicates a significant overall or interaction effect, as per RMANOVA.).

Factor 1 (n) Factor 2
Average WMI Errors
Significance
[Test, p]
Exposure/Treatment Trial * Interaction effect
[RMANOVA, p < 0.001]
1 2 3 4
Sham + Vehicle (n = 22) 0.336 1.664 3.136 8.018
HI + Vehicle (n = 20) 0.700 3.050 6.130 * 14.870 * * vs. Sham in trials 3 and 4
[t-tests, p < 0.001]
HI + IAIPs (n = 25) 0.374 2.685 6.138 * 14.438 * * vs. Sham in trials 3 and 4
[t-tests, p < 0.001]
Experience Group Trial * Interaction effect
[RMANOVA, p < 0.05]
1 2 3 4
Juvenile (n = 34) 0.548 2.293 4.896 11.456
Adolescent (n = 33) 0.392 2.639 5.373 13.428 NS [t-tests, p > 0.05]
Experience Group
(total)
Week * Interaction effect
[RMANOVA, p < 0.001]
1 2 3 4 5
Juvenile (n = 34) 6.883 4.253 3.398 5.122 4.336
Adolescent (n = 33) 6.571 4.181 4.223 7.655 * 4.660 * vs. juvenile in wk4 [t-tests, p < 0.05]
Sham + Vehicle
Juvenile (n = 11) 5.068 1.955 2.364 2.863 2.159
Adolescent (n = 11) 5.818 2.182 2.068 5.545 * 2.864 * vs. juvenile in wk4 [t-tests, p < 0.05]
HI + Vehicle
Juvenile (n = 10) 9.350 5.900 4.100 5.600 5.425
Adolescent (n = 10) 6.875 5.175 5.225 8.400 * 5.825 * vs. juvenile in wk4 [t-tests, p < 0.05]
HI + IAIPs
Juvenile (n = 13) 6.231 4.903 3.731 6.903 5.423
Adolescent (n = 12) 7.021 5.188 5.375 9.021 * 5.291 * vs. juvenile in wk4 [t-tests, p < 0.05]