Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Dec 17;12(12):3864. doi: 10.3390/nu12123864

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Connections between regulated metabolic pathways in HFoleic and HFepa goups. Genes differentially expressed from HFepa vs. reference and HFoleic vs. reference biological conditions were used to identify related metabolic reactions in MetExplore allowing a complementary exploration of enriched metabolic pathways. Metabolic reactions associated with modulated genes in both HFepa and HFoleic conditions were mapped in the Mus musculus metabolic network. (a) The Figure shows a global network of mapped metabolic reactions. Reactions in red are HFoleic-related; reactions in green are HFepa-related; blue reactions are both regulated in HFoleic and HFepa groups. Represented metabolic pathways correspond to metabolic pathways enriched with reactions present in the EPA condition ⁽¹⁾, in the oleic condition ⁽²⁾ or in both conditions ⁽³⁾. (b) Representation of the number of identified reactions and the significantly enriched related metabolic pathways according to the MetExplore analysis in the two comparisons that exhibited significant differential gene expression (HFoleic vs. reference and HFepa vs. reference).