Table 1.
Parameter- | Reference | HFoleic | HFepa | ||||||
---|---|---|---|---|---|---|---|---|---|
Body Weight (g) | 26.7 | ± | 0.9 | 36.1 | ± | 1 *** | 33.8 | ± | 2.7 ** |
Fat % | 16 | ± | 1 | 32 | ± | 1 *** | 24 | ± | 3 ** † |
Lean % | 79 | ± | 1 | 64 | ± | 1 *** | 72 | ± | 3 ** †† |
Liver (gram) | 0.87 | ± | 0.04 | 1.11 | ± | 0.04 * | 0.99 | ± | 0.09 |
AUCglucose (a.u.) | 171 | ± | 6 | 207 | ± | 11 * | 196 | ± | 8 |
Glucose (mg/dL) | 195.6 | ± | 13.1 | 274.2 | ± | 13.1 ** | 228.1 | ± | 14.0 † |
Insulin (pg/mL) | 68.6 | ± | 8.3 | 182.8 | ± | 18.8 *** | 109.4 | ± | 25.9 † |
TAG (g/L) | 0.310 | ± | 0.013 | 0.366 | ± | 0.024 | 0.378 | ± | 0.039 |
T Cholesterol (g/L) | 0.926 | ± | 0.034 | 1.116 | ± | 0.050 * | 1.166 | ± | 0.068 * |
Glycerol (µM) | 213.1 | ± | 11.9 | 237.2 | ± | 19.0 | 257.1 | ± | 24.0 |
Nefa (mM) | 0.350 | ± | 0.038 | 0.228 | ± | 0.029 | 0.404 | ± | 0.081 |
Data are mean ± SEM (n = 9, 8 and 7 mice in Ref, HFoleic and HFepa, respectively). * p < 0.05 vs. Ref; ** p < 0.01 vs. Ref; *** p < 0.001 vs. Ref; † p < 0.05 vs. HFoleic; †† p < 0.01 vs. HFoleic. TAG, triacylglycerols; Nefa, non-esterified fatty acids.