Table 2.
Univariate Cox regression analysis of recurrence within 10 years after breast cancer surgery (N = 1140).
| Variables | HR (95% CI) | p Value |
|---|---|---|
| Demographic characteristics | ||
| Age, years | 0.97 (0.97–0.98) | <0.001 |
| Education, years | 0.88 (0.87–0.90) | <0.001 |
| Current residence with family member(s) (no vs. yes) | 0.25 (0.22–0.29) | <0.001 |
| Marital status (unmarried vs. married) | 0.47 (0.44–0.51) | <0.001 |
| Body mass index, kg/m2 | 0.95 (0.94–0.95) | <0.001 |
| Charlson Comorbidity Index, score | 0.62 (0.57–0.68) | <0.001 |
| Tumor size, cm | 0.66 (0.62–0.70) | <0.001 |
| Tumor stage | ||
| I vs. 0 | 0.19 (0.15–0.26) | < 0.001 |
| II vs. 0 | 0.19 (0.15–0.24) | <0.001 |
| ≥III vs. 0 | 0.47 (0.36–0.62) | <0.001 |
| Smoker (no vs. yes) | 0.46 (0.26–0.81) | 0.007 |
| Drinker (no vs. yes) | 0.11 (0.34–0.37) | <0.001 |
| Breast cancer history (no vs. yes) | 0.34 (0.24–0.49) | <0.001 |
| Clinical characteristics | ||
| Surgery type | ||
| BCS | 0.31 (0.16–0.63) | <0.001 |
| MRM | 2.00 (1.47–2.73) | <0.001 |
| Mastectomy with reconstruction | 0.75 (0.56–1.00) | 0.050 |
| ASA score | 0.50 (0.47–0.54) | <0.001 |
| Chemotherapy (no vs. yes) | 0.28 (0.24–0.33) | <0.001 |
| Radiotherapy (no vs. yes) | 0.28 (0.23–0.33) | <0.001 |
| Hormonal therapy (no vs. yes) | 0.24 (0.20–0.30) | <0.001 |
| Surgeon volume (medium vs. low) | 0.98 (0.98–0.99) | <0.001 |
| Surgeon volume (high vs. low) | 0.97 (0.97–0.98) | <0.001 |
| Hospital volume (medium vs. low) | 0.98 (0.98–0.99) | <0.001 |
| Hospital volume (high vs. low) | 0.97 (0.97–0.98) | <0.001 |
| Quality of care within 10 years | ||
| Readmission in 30 days (no vs. yes) | 0.23 (0.17–0.31) | <0.001 |
| Postoperative reconstruction (no vs. yes) | 0.50 (0.35–0.72) | <0.001 |
| Preoperative quality of life | ||
| Preoperative SF36 PCS score | 0.97 (0.96–0.97) | <0.001 |
| Preoperative SF36 MCS score | 0.98 (0.97–0.98) | <0.001 |
HR: hazards ratio; BCS: breast conserving surgery; MRM: modified radical mastectomy; ASA: American Society of Anesthesiologists; PCS: physical component summary; MCS: mental component summary.