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. 2020 Dec 17;12(12):3817. doi: 10.3390/cancers12123817

Table 6.

Performance indices of forecasting models when using the validating dataset (n = 171) to predict recurrence within 10 years after breast cancer surgery (unit: %) *.

Models Sensitivity Specificity PPV NPV Accuracy AUROC
ANN 88.90 95.52 84.21 96.97 94.12 97.62
(86.69–91.11) (94.87–96.17) (82.67–85.75) (95.57–98.38) (93.01–95.23) (96.83–98.41)
KNN 46.15 76.66 46.15 76.67 67.44 61.40
(35.14–57.16) (71.48–81.84) (35.24–57.06) (65.69–87.65) (61.12–73.76) (55.41–67.39)
SVM 70.37 94.35 75.50 93.13 89.79 82.40
(65.67–75.07) (93.24–95.46) (70.49–80.51) (92.01–94.25) (88.12–91.46) (81.12–83.68)
NBC 100.00 0.00 19.01 0.00 19.01 50.00
(99.94–100.00) (0.00–0.00) (9.98–28.04) (0.00–0.00) (9.57–28.45) (39.68–60.32)
COX 20.93 0.60 6.62 0.23 5.29 10.50
(7.93–33.95) (0.00–1.01) (4.32–8.92) (0.10–0.36) (3.37–7.21) (4.78–16.22)
p value <0.001 <0.001 <0.001 <0.001 <0.001 <0.001

ANN: artificial neural network; KNN: k-nearest neighbor; SVM: support vector machine; NBC: naïve Bayesian classifier; PPV: positive predictive value; NPV: negative predictive value; AUROC: area under the receiver operating characteristic curve. * 1000 pairs of forecasting models with bootstrapping methods were compared in terms of accuracy in predicting recurrence within 10 years after breast cancer surgery.