Table 3.

Twenty seven proteins were identified from wound exudates carrying oxidative modifications on tyrosine (oxidation/+15.99 Da, nitrosylation/+28.99 Da, nitration/+44.99 Da). The total number of proteins found with modification was 80 out of 308 proteins identified. Blood-derived proteins dominate the list. Modifications occur predominantly at the protein surface.

Uniprot Identifier	Abbreviated Protein Name	Protein Name	Modified Tyrosine Residue (Bold Denotes Significant Site)
P02768	ALBU	Albumin	Y54, Y172, Y174, Y287, Y377, Y425, Y356, Y365, Y521
P01009	A1AT	Alpha-1-antitrypsin	Y184
P01023	A2MG	Alpha-2-macroglobulin	Y544, Y818, Y1152, Y1264
O43299	AP5Z1	AP-5 complex subunit zeta-1	Y344
P02647	APOA1	Apolipoprotein A-I	Y124, Y190
P00915	CAH1	Carbonic anhydrase 1	Y21
P00450	CERU	Ceruloplasmin	Y55, Y539
P01024	CO3	Complement C3	Y139, Y1447, Y1620
P0C0L4	CO4A	Complement C4-A	Y1612
P02751	FINC	Fibronectin	Y841, Y2362
P00738	HPT	Haptoglobin	Y224, Y242, Y280, Y386, Y389
P69905	HBA	Hemoglobin subunit alpha	Y25, Y43
P68871	HBB	Hemoglobin subunit beta	Y36, Y131
P02042	HBD	Hemoglobin subunit delta	Y36, Y131
P01876	IGHA1	Immunoglobulin heavy constant alpha 1	Y276
P01857	IGHG1	Immunoglobulin heavy constant gamma 1	Y161, Y319
Q14624	ITIH4	Inter-alpha-trypsin inhibitor heavy chain H4	Y157
P13645	K1C10	Keratin, type I cytoskeletal 10	Y172, Y325
P02533	K1C14	Keratin, type I cytoskeletal 14	Y46
P35527	K1C9	Keratin, type I cytoskeletal 9	Y330, Y345
P04264	K2C1	Keratin, type II cytoskeletal 1	Y266, Y295, Y358, Y373
Q7Z794	K2C1B	Keratin, type II cytoskeletal 1b	Y361
P35908	K22E	Keratin, type II cytoskeletal 2	Y563, Y589
P02788	TRFL	Lactotransferrin	Y211, Y545
P32119	PRDX2	Peroxiredoxin-2	Y126
P00747	PLMN	Plasminogen	Y66
P02787	TRFE	Serotransferrin	Y114, Y333, Y533