Figure 6.

Heterozygous deletion of β-catenin activates glucose metabolism in the heart. (A) Western blot of total GLUT-4, PDK1 in LV lysates from WT/WT and WT/CKO mice in sedentary conditions (Control) and after the endurance training (Training). (B) Densitometry of GLUT-4 protein normalized to GAPDH. (C) Densitometry of PDK1 protein normalized to GAPDH. The data are expressed as the mean ± SD of arbitrary fold of change relative to control levels. n = 5/group. * p < 0.05, ** p < 0.01 (Kruskal-Wallis test followed by Dunn’s multiple-comparison post hoc test).