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. 2020 Dec 20;12(12):3055. doi: 10.3390/polym12123055

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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In vivo anti-tumor activity of G23-Dox/alg-Fe₃O₄ NPs. (A) Schematic representation of synthesis process and BBB penetrating Dox delivery. (B) In vivo MRI contrast imaging abilities of alg-Fe₃O₄ NPs and G23-alg-Fe₃O₄ NPs. (C) In vivo luminescence images show from U87MG-luc2 cells monitored using the IVIS imaging system after mice were intravenously injected with G23-Dox/alg-Fe₃O₄ NPs for seven days. (D) Body weights of mice during the treatment. Reproduced with permission from Reference [69].