Table 3.
Spearman’s correlations between HRV derived parameters, inflammatory markers, and PROs (n = 55).
| hsCRP | IL-6 | TNF-α | MPO | SLEDAI | SDI | PSS | BDI | MFI-General Fatigue | MFI-Physical Fatigue | MFI-Reduce Activity | MFI-Reduce Motivation | MFI-Mental Fatigue | SF-36 Physical Component | SF-36 Mental Component | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SDNN | −0.05 | −0.11 | −0.21 | 0.04 | −0.21 | −0.14 | 0.16 | −0.11 | 0.05 | −0.14 | −0.10 | −0.08 | −0.06 | −0.03 | −0.01 |
| RMSSD | −0.09 | −0.14 | −0.17 | −0.01 | −0.19 | −0.03 | 0.04 | −0.04 | 0.06 | −0.09 | 0.03 | 0.03 | 0.04 | 0.05 | −0.05 |
| pNN50 | −0.06 | −0.14 | −0.14 | 0.05 | −0.09 | −0.06 | 0.16 | −0.06 | 0.10 | −0.09 | 0.05 | −0.02 | 0.04 | 0.07 | −0.04 |
| LF | −0.03 | −0.08 | −0.23 | −0.08 | −0.16 | −0.17 | 0.17 | −0.13 | 0.10 | −0.08 | −0.10 | −0.13 | −0.05 | −0.03 | 0.01 |
| HF | −0.07 | −0.20 | −0.23 | −0.08 | −0.25 | −0.15 | 0.05 | −0.14 | −0.05 | −0.25 | −0.13 | −0.03 | −0.03 | 0.03 | −0.07 |
| LFHF | 0.05 | 0.32 * | 0.17 | 0.20 | 0.17 | 0.03 | 0.08 | 0.12 | 0.14 | 0.30 * | −0.13 | −0.05 | −0.05 | −0.11 | 0.17 |
| SD1 | −0.09 | −0.14 | −0.17 | −0.01 | −0.19 | −0.03 | 0.04 | −0.04 | 0.06 | −0.09 | −0.03 | 0.04 | 0.04 | 0.05 | −0.05 |
| SD2 | −0.03 | −0.09 | −0.21 | 0.09 | −0.20 | −0.17 | 0.18 | −0.14 | 0.06 | −0.14 | 0.03 | −0.09 | −0.09 | −0.05 | 0.00 |
| SampEn | −0.35 ** | −0.16 | −0.16 | −0.32 * | −0.03 | −0.05 | −0.19 | 0.15 | 0.05 | 0.04 | −0.12 | 0.23 | 0.23 | 0.14 | 0.14 |
Notes: * p < 0.05; ** p < 0.01. BDI, Beck depression inventory; HF, high frequency power; hsCRP, high sensitivity C-reactive protein; IL-6, interleukin-6; LF, low frequency power; MFI, multidimension fatigue inventory; MPO, myeloperoxidase; pNN50, percentage of successive normal sinus RR intervals more than 50 ms; PSS, perceived stress scale; RMSSD, root mean square successive difference; SampEn, sample entropy; ms. milliseconds; SD1, standard deviation—poincaré plot crosswise; SD2, standard deviation—poincaré plot lengthwise; SDI, systemic damage index; SDNN, standard deviation of NN intervals; SF-36, short form health survey; SLEDAI, systemic lupus erythematosus disease activity index; TNF-α, tumor necrosis factor alpha.