Figure 2.

The effects of compounds 10b and 13b on the latency time in the tail-flick test. Morphine was used as a reference drug. All compounds were administered intragastrically. Experimental groups (n = 12): C—control group; M—group receiving 10 mg/kg of morphine; 10b-5, 10b-10, 10b-20—groups receiving, respectively, 5, 10, or 20 mg/kg of investigated compound 10b; 13b-5, 13b-10, 13b-20—groups receiving, respectively, 5, 10, or 20 mg/kg of investigated compound 13b. Data are presented as mean ± SEM. Differences ** p < 0.01 vs. control group; *** p < 0.001 vs. control group; ### p < 0.001 vs. morphine group; #### p < 0.0001 vs. morphine group were deemed statistically significant.