Figure 3.

The effects of compounds 10b and 13b on the licking time in the early (0–5 min) and late (25–30 min) phases of the formalin test. Morphine and indomethacin were used as reference drugs. All compounds were administered intragastrically. Experimental groups (n = 12): C—control group; M—group receiving 10 mg/kg of morphine; I—group receiving 10 mg/kg of indomethacin; 10b-5, 10b-10, 10b-20—groups receiving, respectively, 5, 10, or 20 mg/kg of investigated compound 10b; 13b-5, 13b-10, 13b-20—groups receiving, respectively, 5, 10, or 20 mg/kg of investigated compound 13b. Data are presented as mean ± SEM. Differences * p < 0.05 vs. control group; ** p <0.01 vs. control group; *** p < 0.001 vs. control group; # p < 0.05 vs. morphine group; ^ p < 0.05 vs. indomethacin group were deemed statistically significant.