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. 2020 Dec 18;12(12):1235. doi: 10.3390/pharmaceutics12121235
ACT artemisinin combination therapy
ADI acceptable daily intake
ALA alpha-linolenic acid;
API active pharmaceutical ingredients
ARA arachidonic acid
ATP adenosine triphosphate
BBB blood–brain barrier
Cas9 CRISPR-associated protein 9
CD44 cluster of differentiation 44;
CMC critical micellar concentration
CPP cell penetrating peptides
CRISPR clustered regularly interspaced short palindromic repeats
DCC dicyclohexylcarbodiimide
DHA docosahexaenoic acid
DMAP 4-(dimethylamino)pyridine
DOTAP 1,2-dioleoyl-3-trimethylammonium-propane chloride
DPA docosapentaenoic acid
DPPC 1,2-dipalmitoyl-sn-glycero-3-phosphocholine
DSC differential scanning calorimetry
DSPE-PEG2000 1,2-distearoyl-sn-glycero-3-phosphoethanol-amine-N-amino(polyethylene glycol)2000
ELISA enzyme-linked immunosorbent assay
EPR enhanced permeability and retention
ESR electron spin resonance
EV extracellular vesicles
FDA US Food and Drug Administration
FTIR Fourier-transform infrared
GI gastrointestinal
GIXD grazing incidence X-ray diffraction
GPC glycerophosphocholine
GRAS generally recognized as safe
HA hyaluronic acid
HLD hydrophilic–lipophilic deviation
HSC hepatic stellate cells
HSPC hydrogenated soybean phosphatidylcholine
i.m. intramuscular
i.v. intravenous
ITC isothermal titration calorimetry
LLOD lower limit of detection
LPE lyso-phosphatidylethanolamine
miRNA micro ribonucleic acid
ML-I mistletoe-lectin-I
MM mixed micelles
MM-DDS mixed micellar drug delivery systems
MNBA 2-methyl-6-nitrobenzoic anhydride
MPS mononuclear phagocytic system
mRNA messenger ribonucleic acid
MTP-PE muramyl tripeptide
NAFLD non-alcoholic fatty liver disease
NASH non-alcoholic steatohepatitis
NIR near-infrared
NSAID non-steroidal anti-inflammatory drugs
o/w oil-in-water
OXIL oxidation-responsive liposomes
OxPL oxidized phospholipids
PA phosphatic acid
PC phosphatidylcholine
PE phosphatidylethanolamine
PEG polyethylene glycol
PG phosphatidylglycerol
PI phosphatidylinositol
PLA1 phospholipase A1 (alternatively A2, B, C, D)
PLGA poly(lactide-co-glycolide)
POPC 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine
PRC Phospholipid Research Center Heidelberg
PRR pattern-recognition-receptor
PS phosphatidylserine
PUFA polyunsaturated fatty acids
RNA ribonucleic acid
s.c. subcutaneous
SANP self-assembling nanoparticle
SAXS small angle X-ray scattering
SEDDS self-emulsifying drug delivery systems
siRNA small interfering ribonucleic acid
SLN solid-lipid nanoparticles
SM sphingomyelin
SNEDDS self nano-emulsifying drug delivery systems
SPM specialized pro-resolving mediators
TAM tumor-associated macrophages
TB tuberculosis
TEL tetraether lipid
TRXF total reflection X-ray fluorescence
TSL temperature-sensitive liposomes
USL ultrasound-sensitive liposomes
USP United States Pharmacopeia
w/o water-in-oil
WHO World Health Organization