Relative mRNA-expression und protein expression of proinflammatory factors in PXE fibroblasts and NHDF. Fibroblasts were cultivated for 21 d in medium with 10% FCS or 10% LPDS. (A) Relative IL6 mRNA-expression of PXE fibroblasts (gray, n = 3) and NHDF (white, n = 3). (B) IL6 protein concentration in supernatants of PXE fibroblasts (gray, n = 3) and NHDF (white, n = 3). (C) Relative MCP1 mRNA-expression of PXE fibroblasts (gray, n = 3) and NHDF (white, n = 3). (D) MCP1 protein concentration in supernatants of PXE fibroblasts (gray, n = 3) and NHDF (white, n = 3). (E) Relative ICAM1 mRNA-expression of PXE fibroblasts (gray, n = 3) and NHDF (white, n = 3). Data are shown as mean ± SEM. Control/PXE: *** p ≤ 0.001; ns p > 0.05. 10% FCS/10% LPDS: # p ≤ 0.05; ns p > 0.05.