Figure 3.

RL1 mechanistic effects. (a) Cell cycle arrest in the G0/G1 phase of all the models given DNA content %, (b) small apoptosis increase in all cell lines only statistically significant in NCH644 and BTSC233, with numerical increase in the other cell lines, (c) significant decrease in GSC proliferation given by Ki67% expression. Statistical tests performed for two variables with the unpaired Student’s t-test. The significance of the difference between groups was described as * p < 0.05, ** p < 0.01, # numerical-nonsignificant.