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. 2020 Dec 21;12(12):3862. doi: 10.3390/cancers12123862

Table 2.

Studies reporting TMEFF2 intracellular localization.

Cells Antibody or Detection Method Used Intracellular Location Ref.
PC3 Pr1#19 Membranous and punctate-cytoplasmic [47]
PC3 2H8 Membranous and punctate-cytoplasmic upon internalization, co-localizes with acidic organelles [52]
MC65 48G2 Perinuclear and punctate-cytoplasmic, not membranous [7]
22Rv1 Abcam
(details not mentioned)
Punctate-cytoplasmic along the rim of the nucleus when tested though immunofluorescence; membranous, cytoplasmic and nuclear in cell fractionation [21]
HEK293T Not mentioned Membranous and diffused-cytoplasmic upon immunofluorescence but exhibits mitochondrial appearance when fusion constructs were used [53]
22Rv1 Abcam
(details not mentioned)
Membranous, cytoplasmic, nuclear; colocalization with β-actin and α-tubulin [20]
LnCaP GFP-fusion construct Membranous and diffused-cytoplasmic for full length and punctate-cytoplasmic for short secreted isoform [13]