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. 2020 Dec 20;10(12):2559. doi: 10.3390/nano10122559

Table 2.

Effect concentrations derived from concentration-response curves of the single nanoparticles and the mixtures a.

Materials Scenedesmus obliquus Chlorella pyrenoidosa
Single Toxicity EC10 (mg/L) EC50 (mg/L) EC10 (mg/L) EC50 (mg/L)
TiO2 NPs 2.33 19.75 0.13 5.38
[1.75–3.44] [17.02–23.00] [0.11–0.14] [3.36–8.23]
TiO2 NTs 13.16 211.26 0.002 4.87
[5.08–25.75] [152.01–427.73] [0.002–0.004] [2.81–9.66]
Combined Toxicity EC50 (mg/L) EC50 (mg/L)
TiO2
NPs + NTs
OBS 85.04 [69.50–102.54] 2.05 [1.16–3.88]
IA 56.30 [56.17–56.42] 1.08 [0.91–1.34]
CA 99.46 [99.09–99.81] 5.96 [4.97–7.36]

a EC10/EC50 = 10%/mean effect concentration. The 95% two-sided confidence interval is shown in []; OBS = observed combined toxicity; IA = independent action; CA = concentration addition.