Table 1.
Virus-like particle (VLP) mediated RNA delivery.
| Virus Type | Capsid Modification | RNA Package | Copy Number | Addgene Plasmids | Reference |
|---|---|---|---|---|---|
| LV | Not modified | TALEN mRNA | 2 copies | LeGO-iG2-wPRE-pA (60489) | [45] |
| LV | MCP replaced the second zinc finger domain of NC | SpCas9 mRNA | ~6 copies | Not available | [46] |
| Murine Leukemia Virus | Two copies of MCP replaced NC | SpCas9 mRNA and sgRNA | Not available | Not available | [47] |
| LV | MCP inserted after the second zinc finger domain of NC | SaCas9 mRNA | 50~100 copies | pSaCas9-1xms2-2x3′UTR (122946) | [48] |
| pSaCas9-1xPP7-2x3′UTR(122947) | |||||
| psPAX2-D64V-NC-PP7(122945) | |||||
| psPAX2-D64V-NC-MS2(122944) | |||||
| Foamy Viruses | Not modified | SpCas9 mRNA | 60 copies | Not available | [49] |