Table 1.
Gene Ontology (GO) pathways affected by PB.
| Increased Expression | Reduced Expression | |||
|---|---|---|---|---|
| Pathway | p-Value | Pathway | p-Value | |
| High PB | Nonsense-mediated decay | 9.66 × 10−15 | Monocarboxylic acid transport | 5.89 × 10−4 |
| SRP-dep cotrln protein targeting | 7.28 × 10−15 | Multicellular organismal signaling | 3.71 × 10−4 | |
| Cytoplasmic translation | 5.74 × 10−9 | Action potential | 3.13 × 10−4 | |
| Ribosomal large subunit assembly | 3.98 × 10−4 | |||
| Low PB | Regulation of transcription | 2.9 × 10−12 | Cellular amino acid catabolic process | 3.91 × 10−5 |
| Embryonic skeletal morphogenesis | 3.92 × 10−6 | Export across plasma membrane | 3.52 × 10−4 | |
| Nuclear division | 1.08 × 10−4 | Selective autophagy | 3.4 × 10−4 | |
| Neg regulation of axonogenesis | 1.26 × 10−4 |