Table 7.
Sensitivity, specificity, positive and negative predictive values, positive and negative likelihood ratio, and correlation with a positive outcome (PO for diagnosis of cystitis) using different criteria (mean and 95% CI). CI, confidence interval; PPV, positive predictive value, NPV, negative predictive value; +LR, positive likelihood ratio; −LR, negative likelihood ratio; AUC, area under the curve; PO, positive outcome (diagnosis is correct). Main symptoms and 3 EMA symptoms: urinary frequency, urinary urgency, dysuria; 4 FDA symptoms: urinary frequency, urinary urgency, dysuria, suprapubic pain.
| Criteria | N (%) Positive |
N (%) Negative |
Sensitivity | Specificity | PPV | NPV | +LR | −LR | AUC | Correlation with PO |
|---|---|---|---|---|---|---|---|---|---|---|
| ACSS: typical domain, sumscore ≥6 |
96 (96%) |
2 (2%) |
0.96 (0.90–0.99) |
0.98 (0.93–1.00) |
0.98 (0.92–1.00) |
0.96 (0.90–0.99) |
48.00 (12.17–189.38) |
0.04 (0.02–0.11) |
0.97 (0.95–0.99) |
0.94 (0.92–0.95) |
| ACSS: main symptoms, sumscore ≥6 |
77 (77%) |
1 (1%) |
0.77 (0.68–0.85) |
0.99 (0.95–1.00) |
0.99 (0.93–1.00) |
0.81 (0.73–0.88) |
77.00 (10.92–542.88) |
0.23 (0.16–0.33) |
0.88 (0.84–0.92) |
0.78 (0.72–0.83) |
| FDA: at least 2 positive symptom of 4 |
100 (100%) |
33 (33%) |
1.00 (0.96–1.00) |
0.67 (0.57–0.76) |
0.75 (0.67–0.82) |
1.00 (0.95–1.00) |
3.03 (2.29–4.01) |
0.00 (0.00-NA) |
0.84 (0.79–0.88) |
0.71 (0.63–0.77) |
| EMA: at least 1 positive symptom of 3 |
100 (100%) |
22 (22%) |
1.00 (0.96–1.00) |
0.78 (0.69–0.86) |
0.82 (0.74–0.88) |
1.00 (0.95–1.00) |
4.55 (3.14–6.57) |
0.00 (0.00-NA) |
0.89 (0.85–0.93) |
0.80 (0.74–0.85) |