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. 2020 Dec 18;9(12):4092. doi: 10.3390/jcm9124092

Figure 2.

Figure 2

Figure 2

(A–C): PARK2 protein concentration. PARK2 protein concentration was evaluated in HDF lines (A + B) and mDANs (C) in baseline conditions and after 24 h nutrient deprivation (=starvation) stress and after treatment with 10 µM CCCP for 24 h. PARK2 protein data were obtained from two independent experiments (HDF, only one experiment in mDAN) with samples measured in duplicates. Data are shown as mean ± SEM. Exploratory ANOVA was calculated. A show the data from HDF cell lines from PARK2 CNV duplication vs. deletion vs. wildtype healthy control separately, C shows a combined analysis of HDF data of PARK2 CNV deletion + duplication vs. wildtype ADHD + healthy to increase number of cell lines and statistical power. Level of significance was set at p = 0.05. * p ≤ 0.05; *** p ≤ 0.001.