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. 2020 Dec 21;10(12):1017. doi: 10.3390/brainsci10121017

Table 2.

Severity and outcomes of COVID-19 based on neurological pathophysiology confirmed through MRI findings for patients (n = 171).

Pathophysiology N Severe
n (%)
Non-Severe
n (%)
p-Value Fatal
n (%)
Non-Fatal
n (%)
p-Value
Ischemic stroke
Non-ischemic stroke
62
109
35(36)
61(64)
27(36)
48(64)
0.951 25(51)
24(49)
37(30)
85(70)
0.011 *
Hemorrhagic stroke
Non-hemorrhagic stroke
41
130
30(31)
66(69)
11(15)
64(85)
0.012 * 17(35)
32(65)
24(20)
98(80)
0.037 *
Encephalitis
Non-encephalitis
24
147
17(18)
79(82)
7(9)
68(91)
0.118 3(6)
46(94)
21(17)
101(83)
0.059
CNS inflammatory
Non-inflammatory
44
127
24(25)
72(75)
20(27)
55(73)
0.805 11(22)
38(78)
33(27)
89(73)
0.534
Encephalopathy
Non-encephalopathy
11
160
11(11)
85(89)
0(0)
75(100)
0.002 * 6(12)
43(88)
5(4)
117(96)
0.049 *
GBS and its variant
Non-GBS
3
168
1(1)
95(99)
2(3)
73(97)
0.422 0(0)
49(100)
3(2)
119(98)
0.268
Olfactory bulb enhancement
No olfactory bulb enhancement
3
168
0(0)
96(100)
3(4)
72(96)
0.048 * 0(0)
49(100)
3(2)
119(98)
0.268
Other cranial nerve enhancement
Non-cranial nerve enhancement
6
165
0(0)
96(100)
6(8)
69(92)
0.005 * 0(0)
49(100)
6(5)
116(95)
0.114
Others (Yes)
Others (No)
6
165
4(4)
92(96)
2(3)
73(97)
0.597 3(6)
46(94)
3(2)
119(98)
0.239

* p-value significant (bold) at <0.05.