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. 2020 Dec 18;21(24):9694. doi: 10.3390/ijms21249694

Figure 4.

Figure 4

(A,B) TCs/CD34+SCs in neuromas. (A): a nerve fascicle between adipocytes (ad), TCs (arrows) are observed around and within the fascicle in a semithin section stained with toluidine blue. (B): ultrastructural image showing TC telopodes (arrows) around nerve fibres. Ultrathin section. Uranyl acetate and lead citrate. Inserts in (A,B), TCs/CD34+SCs (green) and Schwann cells (red) shown by double immunofluorescence labelling for CD34 (green) and S100 protein (red). (C,D): TCs/CD34+SCs (green) around nerve fibres and neuro-glial units (arrows) (red) between adipocytes (ad) in a hyperplastic neurogenic process. Double immunofluorescence labelling for CD34 (green) and calretinin ((C), red) or synaptophysin ((D), red). Bar: (A,C,D): 40 µm; (B): 4 µm; inserts of (A) and (B): 50 µm.