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. 2020 Dec 18;12(12):1230. doi: 10.3390/pharmaceutics12121230

Table 2.

The drugs researched for brain tumor therapeutics via intranasal nanoemulsions.

Drug Method of Preparation GS and ZP In Vivo Model Ref.
Ecto-50-nucleotidase
(CD73)
Microfluidization 262.7 ± 12.8 nm
+3.5 ± 3.0
C6 rat glioma [111]
Kaempferol High-pressure homogenization 180.53 ± 4.90 nm (coated)
+26.09 ± 2.67 (coated)
145.07 ± 4.91 nm (uncoated)
−18.10 ± 2.55 (uncoated)
N/A [112]
Temozolomide High-pressure
homogenization
134 nm
−13.11
N/A [113]