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Effect of size of PLGA-PEG NPs on percent platelet aggregation (% PA) of platelets in PRP induced by ADP; ADP was added at a final concentration of 20 µM for 12 min after incubation with PLGA-PEG NPs of different sizes for 4 min. Values are mean of n = 4–5 ± SEM. One-way ANOVA and Tukey’s multiple comparison tests were used for analysis. **** p < 0.0001 for 321 and 585 nm NPs at ≥0.25 and ≥0.50 mg/mL respectively.
